COVID-19 patients who do not show symptoms may have low levels of immunity: study

PARIS: People who catch COVID-19, but do not show symptoms, may have significantly lower levels of immunity than viruses that become seriously ill, new research showed on Thursday.

Most patients with the virus exhibit relatively minor symptoms of infection, and a small proportion show no symptoms at all.

Very few people are aware of this group, noting that they are less likely to be screened than those who develop severe symptoms, including respiratory problems.

Researchers based in China compared two groups of individuals infected with COVID-19 in Wenzhou district of Chongqing: 37 who showed symptoms vs. 37 who did not.

Researchers analyzed blood samples from both groups a few weeks after recovering and found that only 62.2 percent of the asymptomatic group had short-term antibodies, compared to 78.4 percent of symptomatic patients.

After the eight-week sentence, there was a decline in the presence of antibodies in 81.1 percent of asymptomatic patients, compared to 62.2 percent of symptomatic patients.

What’s more, asymptomatic patients found that 18 pro-anti-inflammatory cell-signaling protein levels are lower than the immunosuppressive group, suggesting a weaker immune response to the novel coronavirus.

The authors of the study, which was published in Nature Medicine, said their findings led to the idea that everyone who was a coronovirus is immune to future infections.

“These data may indicate a risk of using the COVID-19 ‘immunity passport’ and may help promote public health interventions, including social discrimination, sanitation, isolation of high-risk groups and widespread Trials are included, ”he wrote.

Danny Altman, a spokesman for the British Society for Immunology and professor of immunology at Imperial College London, said the research raised an important question to combat COVID-19.

He said, “Most immunology data so far have come from an analysis of the sickest, hospitalized patients, but most people who have been mildly affected want to know if they are likely to get permanent, protective immunity.” “

Altmann said it was “an important and potentially worrying point” that many patients in the study showed a significant drop in antibody levels in just two months.

“While this is a small sample size of patients, it is consistent with some concerns that natural immunity to coronavirus may be quite short-lived,” Altman, who was not involved in the research.

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